The runners-up, with a word from the voters

   
1. miR-380-5p.
 Swarbrick, A. et al. 2010. miR 380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma. Nature Medicine. published online Sept. 2010; doi:10.1038/nm.2227
 Clearly, this is an interesting non-coding RNA. The implication to repress p53 in order to control cellular survival was completely unexpected, and, in fact, is really cool. However, the new finding show that blocki...

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